WHO 2020/9/22まとめ
赤字は中国企業 IM=Intramuscular 筋肉注射 ID=intradermal 皮内注射
Developer/manufacturer | Platform | Type | doses | Timing | Route | Phase | |||
1 | 1/2 | 2 | 3 | ||||||
University of Oxford/AstraZeneca | Non-Replicating Viral Vector | ChAdOx1-S | 1 | IM | 〇 | 〇 | 〇 | ||
CanSinoBiological Inc./Beijing Institute of Biotechnology | Non-Replicating Viral Vector | Adenovirus Type 5 Vector | 1 | IM | 〇 | 〇 | 〇 | ||
Gamaleya Research Institute(ロシア) | Non-Replicating Viral Vector | Adeno-based | 2 |
0, 21 days
|
IM | 〇 | 〇 | ||
Janssen Pharmaceutical (J&J) | Non-Replicating Viral Vector | Ad26COVS1 | 2 | 0,56 days | IM | 〇 | 〇 | ||
Sinovac(中国) | Inactivated | Inactivated | 2 | 0, 14 days | IM | 〇 | 〇 | ||
Wuhan Institute of Biological Products/Sinopharm | Inactivated | Inactivated | 2 |
0,14 or 0,21 days |
IM | 〇 |
〇
|
||
Beijing Institute of Biological Products/Sinopharm | Inactivated | Inactivated | 2 |
0,14 or 0,21 days |
IM | 〇 |
〇
|
||
Moderna/NIAID(米国立アレルギー感染症研究所) | RNA | LNP-encapsulated mRNA | 2 | 0, 28 days | IM | 〇 | 〇 | 〇 | |
BioNTech(独)/Fosun Pharma(上海復星医薬)/Pfizer 〔前2社が提携〕 | RNA | 3 LNP-mRNAs | 2 | 0, 28days | IM | 〇 |
〇
|
||
Novavax(米) | Protein Subunit | Full length recombinant SARS CoV-2 glycoprotein nanoparticle vaccine adjuvanted with Matrix M | 2 | 0, 21 days | IM | 〇 | 〇 | ||
Anhui Zhifei Longcom Biopharmaceutical/Institute of Microbiology, Chinese Academy of Sciences | Protein Subunit | Adjuvanted recombinant protein (RBD-Dimer) | 2 or 3 |
0,28 or 0,28,56 days |
IM | 〇 | 〇 | 〇 | |
Curevac(独) | RNA | mRNA | 2 | 0, 28 days | IM | 〇 | 〇 | ||
Institute of Medical Biology, Chinese Academy of Medical Sciences | Inactivated | Inactivated | 2 | 0, 28 days | IM | 〇 | 〇 | ||
Research Institute fo Bological Safety Problems, Rep. of Kazakhstan | Inactivated | Inactivated | 2 | 0, 21 days | IM | 〇 | |||
InovioPharmaceuticals(米)/ International Vaccine Institute | DNA | DNA plasmid vaccine with electroporation | 2 | 0, 28 days | ID | 〇 | |||
Osaka University/ AnGes/ Takara Bio | DNA | DNA plasmid vaccine + Adjuvant | 2 | 0, 14 days | IM | 〇 | |||
Cadila Healthcare(インド) | DNA | DNA plasmid vaccine | 3 | 0, 28, 56 days | ID | 〇 | |||
Genexine Consortium(韓国) | DNA | DNA Vaccine (GX-19) | 2 | 0, 28 days | IM | 〇 | |||
Bharat Biotech (インド) | Inactivated | Whole-Virion Inactivated | 2 | 0, 14 days | IM | 〇 | |||
Kentucky Bioprocessing(米) | Protein Subunit | RBD-based | 2 | 0, 21 days | IM | 〇 | |||
Sanofi Pasteur/GSK | Protein Subunit | S Protein (baculovirus production) | 2 | 0, 21 days | IM | 〇 | |||
Arcturus(米)/Duke-NUS(シンガポール) | RNA | mRNA | IM | 〇 | |||||
ReiThera(伊)/LEUKOCARE(独)/Univercells(ベルギー) | Non-Replicating Viral Vector | Replication defective Simian Adenovirus (GARs) encoding S | 1 | IM |
〇
|
||||
Institute of Biotechnology, Academy of Military Medical Sciences, PLA of China | Non-Replicating Viral Vector | Ad5-nCoV | 2 | 0, 28 days | IM/mucosal | 〇 | |||
Clover Biopharmaceuticals Inc./GSK/Dynavax | Protein Subunit | Native like Trimeric subunit Spike Protein vaccine | 2 | 0, 21 days | IM | 〇 | |||
Vaxine Pty Ltd(豪)/Medytox(韓) | Protein Subunit | Recombinant spike protein with Advax™ adjuvant | 1 | IM | 〇 | ||||
University of Queensland/CSL(豪)/Seqirus(英) | Protein Subunit | Molecular clamp stabilized Spike protein with MF59 adjuvant | 2 | 0, 28 days | IM | 〇 | |||
Medigen Vaccine Biologics(台湾)/NIAID/Dynavax | Protein Subunit | S-2P protein + CpG 1018 | 2 | 0, 28 days | IM | 〇 | |||
Instituto Finlay de Vacunas, Cuba | Protein Subunit | PBD + Adjutant | 2 | 0, 28 days | IM | 〇 | |||
FBRI SRC VB Vector, Rospotrebnadzor, Koltsovo Russia |
Protein Subunit | Reptide | 2 | 0, 21days | IM | 〇 | |||
West China Hospital, Sichuan University | Protein Subunit | PBD (baculovirus production expressed in Sf9 cells) | 2 | 0, 28 days | IM | 〇 | |||
University Hospital Tuebingen | Protein Subunit | SARS-CoV-2 HLA-DR peptides | 1 | SC | 〇 | ||||
COVAXX (United Biomedical ) | Protein Subunit | S1-RBD-protein | 2 | 0, 28 days | IM | 〇 | |||
Institute Pasteur/Themis/Univ. of Pittsburg CVR/Merck Sharp & Dohme | Replicating Viral Vector | Measles-vector based |
1 or 2 |
0, 28 days | IM |
〇
|
|||
Beijing Wantai Biological Pharmacy/ Xiamen University | Replicating Viral Vector | Intranasal flu-based-RBD | 1 | IM | 〇 | ||||
Imperial College London | RNA | LNP-nCoVsaRNA | 2 | IM | 〇 | ||||
People's Liberation Army (PLA) Academy of Military Sciences/Walvax Biotech(云南沃森生物) | RNA | mRNA | 2 |
0, 14 or 0, 28 days |
IM | 〇 | |||
Medicago(カナダ 田辺三菱製薬) | VLP | Plant-derived VLP adjuvanted with GSK or Dynavax adjs. | 2 | 0, 21 days | IM | 〇 |