The Cosmos Alliance

2003/1/14  http://www.ipo.com/venture/press.asp?p=IPO&prid=2795


The Cosmos Alliance Provides $6.5 Million in Bio Life Funding; Club Arranges Direct Investments and Global Collaboration for Breakthrough Bio Life Sciences Technologies

The Cosmos Alliance, a new model for fostering global investments and business collaborations among club members who are working to develop breakthrough bio life technologies (www.cblsa.com), announced today the successful completion of $6.5 million in investments in December of 2002, which is the first in a series of ongoing investments.
The initial investments were made by four of the organization's corporate members directly to technology members developing promising biotechnology platforms. Alliance members receiving investments were Panacea Pharmaceuticals, Inc. of Gaithersburg, Maryland; Sensatex, Inc. of New York, New York; EluSys Therapeutics, Inc. of Pine Brook, New Jersey; and Acugen Neuropeutics Inc. of Seattle, Washington.
"There is a huge bottleneck in developing bio life science products. Many promising technologies do not advance due to funding challenges," said Frank E. Young, M.D., Ph.D., former commissioner of the U.S. Food and Drug Administration and chairman of the CBLSA. "At the Cosmos Alliance, we are committed to identifying compelling early-stage companies and introducing them to our corporate members for equity investments, joint ventures, out-licensing, technology transfer and collaborative research projects. There are benefits to both the emerging companies and the corporate members. Instead of creating high-risk ventures, we are facilitating the creation of stronger businesses and expediting the development of important biomedical products."
The Cosmos Alliance was launched in August of 2002 by Dr. Young to enable more rapid development of biomedical products, in turn aiding people with life-threatening diseases.
The organization will help get life-saving technologies to people by creating a new mechanism for major international bio life science companies to learn about, invest in and commercially collaborate with small and emerging companies developing platform technologies.
"The Cosmos Alliance offered not only funding, but also its global intelligence network to develop opportunities for collaboration," said Hossein A. Ghanbari, Ph.D., chairman, president, and chief executive officer of Panacea Pharmaceuticals, Inc., one of the first technology members funded by the Alliance. "The Alliance has become our partner in identifying opportunities, developing relationships, and securing partners in Asia, Europe and the U.S."
The Cosmos Alliance is an invitation-only membership organization that connects large bio life science companies to carefully screened small technology, research and development member companies seeking Series B or C round equity investments and/or collaboration opportunities.
The Cosmos Alliance is managed by a Board of Directors lead by Dr. Young, chairman and chief executive officer, and Robert G. Kalik, managing director. Mr. Kalik is a partner in the Washington, D.C. law firm of KalikLewin.
He has more than 20 years of experience representing international and domestic technology and biotechnology related companies and has previously served as the managing director of a merchant bank and as president of a national trade association.
The Cosmos Alliance has partnered with Mitsubishi Corporation to serve as its business integrator to develop corporate membership internationally. As one of the Alliance's first corporate member investors, Mitsubishi was instrumental in securing the founding Alliance members in Japan and is currently working with the Alliance to expand membership to Korea, China, Europe and the United States.

About The Cosmos Bio Life Sciences Alliance

The Cosmos Bio Life Sciences Alliance (CBLSA) is an international cross-industrial "club" designed to develop, promote and foster breakthrough technologies in bio life sciences.
Under the Alliance, research-intensive early stage and emerging companies with breakthrough platform technologies are encouraged to form alliances with well-established companies seeking to move into new fields as well as to harvest returns from equity investments.
Research and development-stage company members join the Alliance to receive research contracts from companies interested in their technology. Finally, universities and other research organization members join the Alliance to present their breakthrough research and technology to Alliance members and to form valuable strategic partnerships.
For more information on the Alliance please visit www.cblsa.com.

About Mitsubishi Corporation

Mitsubishi Corporation is one of the world's most diverse enterprises. Mitsubishi Corporation has decades of experience doing business around the world, experience that has made it more than just a leader in international trade.
The company's seven business groups - New Business Initiatives, IT & Electronics, Energy, Metals, Machinery, Chemicals and Living Essentials - work closely with clients to develop new business opportunities.
Project coordination, sourcing of raw materials, capital investment, and development of sales channels are typical of the ways Mitsubishi Corporation creates value for business partners, customers and shareholders.


Panacea Pharmaceuticals, Inc.     http://www.panaceapharma.com/

Panacea Pharmaceuticals, Inc. is an emerging biopharmaceutical company focused on utilizing functional genomics and proteomics to develop therapeutic agents and diagnostic tests for diseases with substantial unmet clinical need. The Company's product development focus is on novel proteins and biochemcial pathways related to cellular regulation and cell cycle abnormalities in oncology as well as neurodegenerative diseases, particularly Alzheimer's disease and Parkinson's disease.

Through Collaborative Research Agreements with major institutions, Panacea has access to state-of-the-art facilities and partnerships with internationally recognized scientists in the development of its core technologies. Further, agreements with support groups offering expertise in key developmental areas have been forged.

Panacea has also assembled a large group of world-class scientists and physicians for its Scientific and Clinical Advisory Boards, each with selected specialties that will help ensure the expedited development and success of the Company's projects.


Sensatex, Inc       http://www.sensatex.com/

Sensatex is focused on the commercialization of our Sensatex SmarTextile Technology and our SmartShirt System, a wearable solution for moving a wide range of information on and off an active person.

Sensatex has developed groundbreaking Interconnection Technology that allows sensing, monitoring, and information processing devices to be networked together within a fabric.

The Sensatex fabric was first developed by researchers at the Georgia Institute of Technology's School of Textile and Fiber Engineering under the auspices of the US military's 21st Century Land Warrior Program and the Defense Advance Research Projects Agency (DARPA), the R&D arm of the US Department of Defense.

Our technology can be incorporated into any fabric (cotton, lycra, wool, silk, etc.) or blend of fabrics without effecting the look, feel or integrity of the fabric that it is replacing.

The SmartShirt System incorporates advances in textile engineering, wearable computing, and wireless data transfer to permit the convenient collection, transmission, and analysis of personal health and lifestyle data.

Described as "the shirt that thinks," the SmartShirt allows the comfortable measuring and/or monitoring of individual biometric data, such as heart rate, respiration rate, body temperature, caloric burn, and provides readouts via a wristwatch, PDA, or voice. Biometric information is wirelessly transmitted to a personal computer and ultimately, the Internet.


EluSys Therapeutics, Inc.       http://www.elusys.com/

EluSys Therapeutics, Inc. ("EluSys" or the "Company") is focused on the development and commercialization of the EluSys Heteropolymer System (the "Technology" or "HP System"), a novel platform technology to treat a wide variety of blood-borne infections and autoimmune diseases. The HP System should enable the rapid, safe and efficient removal and destruction of viral particles, bacteria, toxins and autoantibodies from the bloodstream by injecting a therapeutic compound into the patient. The HP System may be tailored to remove and destroy members of the major classes of blood-borne pathogen within several hours of administration, thus potentially providing an effective treatment for a broad array of different diseases.

To date, results of experiments conducted in live, non-human primates (monkeys) indicate that the HP drugs dramatically improved the removal (clearance) of various pathogenic substances (viruses, bacterial, toxins, and autoantibodies) from the blood of these animals relative to the rate of removal in the absence of the HP drug. Moreover, several experiments have shown that the clearance rate of a pathogen in the presence of an HP drug is much faster than the clearance rate of that same pathogen in response to an equal dose of the same monoclonal antibody in the form of a free monoclonal antibody (that is, not crosslinked to the anti-CR1 MAb). In one experiment in which the concentration of a model pathogen (a bacterial virus) was reduced approximately one million fold in response to an HP drug in approximately one hour, essentially no change was seen in the concentration of the virus in the monkeys blood when an identical dose of free monoclonal antibody targeting the virus was administered.

Other experiments in monkeys have also indicated that the ability of an HP drug to promote rapid clearance of a pathogen can persist for at least several days after its infusion into the blood circulation of an animal. These results suggest that it may be possible to use HP drugs prophylactically. That is, it may be possible to treat individuals at risk of exposure to pathogens in advance with an HP drug so that if they are exposed, the pathogen will be rapidly cleared and unable to initiate an infection.


Acugen Neuropeutics Inc.       http://www.acugen-neuro.com/

Acugen Neuropeutics Inc. is a new Seattle based biotechnology company which plans to utilize long-term neural cell culture technology to develop various in vitro neural disease models. The company will screen drugs for various neurodegenerative diseases including glaucoma, macular degeneration and Alzheimer's disease in collaboration with other pharmaceutical companies or biotech companies. Acugen Neuropeutics will also focus on developing image based analytical devices and plastic wares for high content cell based screening, which will become especially important in the postgenomics and postproteomics era.